Summary
Researchers have developed a simple blood test to detect pancreatic cancer before it spreads, potentially improving early diagnosis and survival rates. The test uses nanosensors to detect specific enzymes called proteases, which are active in tumors from the early stages. When placed in a blood sample, these nanosensors release a fluorescent molecule if proteases are present, allowing researchers to measure their activity.
In a study using frozen blood samples from 356 individuals, the test correctly identified healthy individuals 98% of the time and detected pancreatic cancer with 73% accuracy, always distinguishing cancer from other pancreatic diseases. While sensitivity needs improvement for clinical use, experts see the test as a promising and translatable advancement in early cancer detection.
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