Article shared by Tom McDermott.jpeg)
A new study from Scotland shows dramatic real-world evidence of the effectiveness of HPV vaccines in preventing cervical cancer. Researchers monitored 450,000 women born 1988-1996 who were eligible for cancer screening. No cases of cervical cancer were detected among women vaccinated against HPV between ages 12-13, even if they only received 1-2 doses. This group included 40,000 women.
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AI summary of the key points from the article:
- No cases of cervical cancer were detected among women vaccinated against HPV between ages 12-13, even if they only received 1-2 doses. This group included 40,000 women.
- Incidence of cervical cancer was 2.5 times lower among women vaccinated between ages 14-22 with the full 3-dose protocol compared to unvaccinated women.
- The dramatic real-world evidence from Scotland on the ability of HPV vaccines to prevent cervical cancer mirrors the goals of initiatives spearheaded by UNICEF and WHO to bring these lifesaving vaccines to girls in lower-income countries.
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A new study from Scotland shows dramatic real-world evidence of the effectiveness of HPV vaccines in preventing cervical cancer. Researchers monitored 450,000 women born 1988-1996 who were eligible for cancer screening. No cases of cervical cancer were detected among women vaccinated against HPV between ages 12-13, even if they only received 1-2 doses. This group included 40,000 women.
Click here for the full article
AI summary of the key points from the article:
- No cases of cervical cancer were detected among women vaccinated against HPV between ages 12-13, even if they only received 1-2 doses. This group included 40,000 women.
- Incidence of cervical cancer was 2.5 times lower among women vaccinated between ages 14-22 with the full 3-dose protocol compared to unvaccinated women.
- The dramatic real-world evidence from Scotland on the ability of HPV vaccines to prevent cervical cancer mirrors the goals of initiatives spearheaded by UNICEF and WHO to bring these lifesaving vaccines to girls in lower-income countries.
- Similar to the situation described in Scotland prior to national vaccination efforts, HPV vaccination rates can be extremely low in poorer nations. Cost is a major barrier, as HPV vaccines can be prohibitively expensive for many families. By working with manufacturers and pooling demand, UNICEF and partners negotiate lower prices.
- In 2021, UNICEF began working with the governments of Ethiopia, Kenya, Malawi, Mozambique, Tanzania, Uganda, Zambia and Zimbabwe to introduce nationwide HPV vaccination programs. This effort aims to reach 4.5 million girls in these countries in 5 years. Additionally, Gavi, the Vaccine Alliance is supporting introduction of the vaccine in 13 countries by 2025.
- The study underscores the importance of early vaccination, before becoming sexually active, as the women with no cancer cases were vaccinated before age 14.
- Uptake of the vaccine is much higher in Scotland (close to 90% in the target age group) compared to the U.S. (around 60%), showing the value of routine school-based immunization programs.
- Uptake of the vaccine is much higher in Scotland (close to 90% in the target age group) compared to the U.S. (around 60%), showing the value of routine school-based immunization programs.
This is a great news Tom. Thanks for sharing it. I am involved raising money from JPN government for polio vaccines and other vaccines for infectious diseased. Happy to know UNICEF is taking the initiative to introduce HPV for adolescent girls in eight countries in Africa. GAVI is to support extension of the programme to 13 countries by 2025. I understand CAVI and GFATM plan to request donors for contribution to the fund probably June-October 2025. I wonder if UNICEF collaborate with GAVI in fund raising. Some thinks UNICEF is somewhat egoistic and raise funds for it self but not for others. on 8 Feb his year UNICEF ExBoard is organising a special session on polio inviting WHO, Rotary International, Bill & Melinda Gate Foundation to the special session. I hope UNICEF does not simply ask for money for itself but for GPEI (Global Polio Eradication Initiative) as well.
ReplyDeleteYoshi, why don't you ask the Japan Government to propose at the next UNICEF Executive Board session to use UNICEF's ever increasing surplus to finance the introduction of HPV?
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